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Vitamin D receptor agonist

Intervention

1 paper2 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funder: National Natural Science Foundation of China
  • Animals1

Outcomes

2

Bone mass

upin mice1

1 study

  1. Vitamin D receptor agonist improves bone mass in mice.

    “significantly improved osteogenesis, bone mass, and other bone parameters”

    Animalsin HFD-fed mice

    Multiomics profiling reveals VDR as a central regulator of mesenchymal stem cell senescence with a known association with osteoporosis after high-fat diet exposure

    International journal of oral scienceMay 22, 2024

Cellular senescence

downin mice1

1 study

  1. Vitamin D receptor agonist decreases cellular senescence in mice.

    “the administration of a VDR activator to HFD-fed mice rescued BMSC senescence”

    Animalsin HFD-fed mice

    Multiomics profiling reveals VDR as a central regulator of mesenchymal stem cell senescence with a known association with osteoporosis after high-fat diet exposure

    International journal of oral scienceMay 22, 2024

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