Unmarried status

1. Unmarried status has no effect on cognitive function in humans (β = -0.22; 95% CI: -0.56, 0.12).

   “(unmarried women: β = -0.22; 95% CI: -0.56, 0.12; p interaction = 0.006)”

   Humanshypertensive patientsfemales

   Association of marital status with cognitive function in Chinese hypertensive patients: a cross-sectional study

   BMC psychiatry·Jul 27, 2022

2. Unmarried status impairs cognitive function in humans (β = -1.55; 95% CI: -1.89, -1.21).

   “A stronger correlation between marital status and a lower MMSE score was statistically significant in men (unmarried men: β = -1.55; 95% CI: -1.89, -1.21) but not women”

   Humanshypertensive patientsmales

   Association of marital status with cognitive function in Chinese hypertensive patients: a cross-sectional study

   BMC psychiatry·Jul 27, 2022

1. Unmarried status is associated with cardiovascular disease in humans (HR 1.24, 95% CI 0.95-1.62).

   “Our results showed no significant differences in CVD incidence among married (HR 1.00, 95% CI 0.84-1.20) and unmarried individuals (HR 1.24, 95% CI 0.95-1.62)”

   Review

   Marital Status as a Factor in Cardiovascular Disease Risk Stratification: A Systematic Review and Meta-Analysis.

   AHA Scientific Sessions 2025 abstract·Nov 3, 2025

More on Cardiovascular disease

1. Unmarried status raises the risk of dementia in humans (OR 1.46, 95% CI 1.06-1.99).

   “After confounder adjusting, unmarried participants exhibited higher odds ratio (OR:1.46, 95 % CI:1.06-1.99) for dementia.”

   Humans

   Association between marital status and dementia among older adults population: the Chinese longitudinal healthy longevity survey

   Geriatric nursing (New York, N.Y.)·Aug 18, 2025

More on Dementia

1. Unmarried status raises the risk of diabetes in humans.

   “not being married, experiencing strain in a spousal relationship, and feeling lonely were associated with increased risk for diabetes onset at follow-up.”

   Humansincident diabetes over 4- to 5-year follow-up4- to 5-year

   Which Social Variables Predict Diabetes Onset? Robust Findings in Two National Surveys

   The Gerontologist·Aug 10, 2024

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1. Unmarried status raises the risk of cognitive impairment in humans (OR = 1.48, 95% CI: 1.03, 2.14).

   “Participants who had never been married had the highest odds of cognitive impairment compared to their married counterparts (model III: OR = 1.48, 95% CI: 1.03, 2.14).”

   Humansnever married vs married, model IIIn = 2,321

   Association between Marital Status and Cognitive Impairment in a Multi-Ethnic Asian Population

   Neuroepidemiology·Mar 14, 2024

More on Cognitive impairment