UMI-77

  • 1 lab in 1 country
  • Funder: National Natural Science Foundation of China
  • Animals1

Outcomes

4

Myeloid-biased CD150high HSCs

upin mice1

1 study
  1. UMI-77 increases myeloid-biased CD150high HSCs in mice.

    Animals

    Targeted Restoration of Mitophagy Reinvigorates Aged Hematopoietic Stem Cells

    Antioxidants & redox signaling5 Aug 2026

More on Myeloid-biased CD150high HSCs

Hematopoietic reconstitution capacity

upin mice1

1 study
  1. UMI-77 improves hematopoietic reconstitution capacity in mice.

    Animalstransplantation assay

    Targeted Restoration of Mitophagy Reinvigorates Aged Hematopoietic Stem Cells

    Antioxidants & redox signaling5 Aug 2026

Oxidative stress and ROS signalling

downin mice1

1 study
  1. UMI-77 decreases oxidative stress and ROS signalling in mice.

    Animalsin aged HSCs

    Targeted Restoration of Mitophagy Reinvigorates Aged Hematopoietic Stem Cells

    Antioxidants & redox signaling5 Aug 2026

More on Oxidative stress and ROS signalling

Mitophagy

upin mouse cells1

1 study
  1. UMI-77 activates mitophagy in mouse cells.

    Cellsin aged HSCs

    Targeted Restoration of Mitophagy Reinvigorates Aged Hematopoietic Stem Cells

    Antioxidants & redox signaling5 Aug 2026

More on Mitophagy

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