UA-30

Intervention

1 paper5 findings

UA-30 extends lifespan and reduces frailty in naturally aged mice; one mouse study also reports reduced muscle atrophy and fibrosis and improved muscle function. All five findings come from one lab and name the National Outstanding Youth Science Fund Project of the National Natural Science Foundation of China as a funder.

  • 1 lab in 1 country
  • Funders: National Natural Science Foundation of China and 1 more
  • Animals1

Outcomes

5

Muscle function

upin mice1

1 study
  1. UA-30 improves muscle function in mice.

    Animalsmuscle

    UA-30 mitigates systemic aging and motor decline by inhibiting RalA signaling in naturally aged mice

    The Journal of experimental medicine16 Sep 2026

Muscle atrophy

downin mice1

1 study
  1. UA-30 decreases muscle atrophy in mice.

    Animals10-wk

    UA-30 mitigates systemic aging and motor decline by inhibiting RalA signaling in naturally aged mice

    The Journal of experimental medicine16 Sep 2026

Fibrosis

downin mice1

1 study
  1. UA-30 decreases fibrosis in mice.

    Animals10-wk

    UA-30 mitigates systemic aging and motor decline by inhibiting RalA signaling in naturally aged mice

    The Journal of experimental medicine16 Sep 2026

Frailty

downin mice1

1 study
  1. UA-30 decreases frailty in mice.

    Animalsin naturally aged mice

    UA-30 mitigates systemic aging and motor decline by inhibiting RalA signaling in naturally aged mice

    The Journal of experimental medicine16 Sep 2026

Lifespan

upin mice1

1 study
  1. UA-30 extends lifespan in mice.

    Animalsin naturally aged mice

    UA-30 mitigates systemic aging and motor decline by inhibiting RalA signaling in naturally aged mice

    The Journal of experimental medicine16 Sep 2026

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