The Journal of Experimental Medicine

UA-30 mitigates systemic aging and motor decline by inhibiting RalA signaling in naturally aged mice

By Bingge Zhang, Ye He, Ruiming Zhang, Xifei Yang

Experiments in miceInterventions

10 weeks

The paper

Bingge Zhang, Ye He, Ruiming Zhang, Xifei Yang

Shenzhen Center for Disease Control and Prevention

The Journal of Experimental Medicine, 16 Sep 2026

doi.org/10.1084/jem.20260071 PubMed 42747887

Signal Transduction and Targeted Therapy3 Oct 2026
Inotodiol preserves muscle mass and function in aged mice
Aging Cell7 Oct 2026
Blocking an enzyme improved muscle strength in mice
Nature Communications9 Oct 2026
Early overfeeding speeds muscle loss and shortens life in mice
FASEB Journal2 Oct 2026
4-Octyl itaconate restores parotid gland function in aging mice