Theaflavin-3-gallate
Theaflavin-3-gallate has been studied in 3 papers since 2020: none in people yet, 2 in animals, 1 review. The research so far is in animals. The newest paper, Sep 13, 2022: “Potential Role of Polyphenolic Flavonoids as Senotherapeutic Agents in Degenerative Diseases and Geroprotection”.
None of its findings points the other way.
- 1 lab in 1 country
- Funders: National Natural Science Foundation of China and 4 more
- Animals2
What did studies of Theaflavin-3-gallate find?
4Studies of Theaflavin-3-gallate measured 4 outcomes; the most studied are bone regeneration (1 study), cellular senescence (1) and aging-associated pathology (1).
Bone regeneration
upin mice1
1 study
Bone regeneration
upin mice1
Theaflavin-3-gallate improves bone regeneration in mice.
“theaflavin 3-gallate could alleviate the senescence of BMSCs and promote bone regeneration in middle-aged mice.”
Animals
PeerJ
Cellular senescence
downin mice1
1 study
Cellular senescence
downin mice1
Theaflavin-3-gallate decreases cellular senescence in mice.
“theaflavin 3-gallate could alleviate the senescence of BMSCs”
Animals
PeerJ
Aging-associated pathology
downin mice1
1 study
Aging-associated pathology
downin mice1
Theaflavin-3-gallate decreases aging-associated pathology in mice.
“Treatment of middle-aged mice with theaflavin 3-gallate reduced the senescence of htNSCs while improving aging-associated pathology.”
Animalsmiddle-aged mice
Reducing Hypothalamic Stem Cell Senescence Protects against Aging-Associated Physiological Decline
Cell metabolism
senescence of hypothalamic neural stem cells
downin mice1
1 study
senescence of hypothalamic neural stem cells
downin mice1
Theaflavin-3-gallate decreases senescence of hypothalamic neural stem cells in mice.
“Treatment of middle-aged mice with theaflavin 3-gallate reduced the senescence of htNSCs while improving aging-associated pathology.”
Animalsmiddle-aged micehypothalamic neural stem cells
Reducing Hypothalamic Stem Cell Senescence Protects against Aging-Associated Physiological Decline
Cell metabolism