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Tensile stress stimulation

Intervention

1 paper studies it4 findings

Across all fields, 1 paper: none in people yet, 1 in cells

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funder: National Natural Science Foundation of China
  • Cells1

Outcomes

4

MIR214

downin human cells1

1 study

  1. Tensile stress stimulation decreases MIR214 in human cells.

    “The results suggested a significant reduction in the expression of miR-210-3p and miR-214-3p triggered by the 3D strain microenvironment in old-JBMSCs.”

    Cells3D strain microenvironmentjaw bone marrow-derived mesenchymal stem cells

    Three-Dimensional Mechanical Microenvironment Rescued the Decline of Osteogenic Differentiation of Old Human Jaw Bone Marrow Mesenchymal Stem Cells

    ACS biomaterials science & engineering

More on MIR214

MIR210

downin human cells1

1 study

  1. Tensile stress stimulation decreases MIR210 in human cells.

    “The results suggested a significant reduction in the expression of miR-210-3p and miR-214-3p triggered by the 3D strain microenvironment in old-JBMSCs.”

    Cells3D strain microenvironmentjaw bone marrow-derived mesenchymal stem cells

    Three-Dimensional Mechanical Microenvironment Rescued the Decline of Osteogenic Differentiation of Old Human Jaw Bone Marrow Mesenchymal Stem Cells

    ACS biomaterials science & engineering

More on MIR210

Cellular senescence

downin human cells1

1 study

  1. Tensile stress stimulation decreases cellular senescence in human cells.

    “this study demonstrated that the 3D strain microenvironment efficiently rescued the cellular senescence of old-JBMSCs via modulating specific miRNAs”

    Cellsin vitro 3D strain microenvironmentjaw bone marrow-derived mesenchymal stem cells

    Three-Dimensional Mechanical Microenvironment Rescued the Decline of Osteogenic Differentiation of Old Human Jaw Bone Marrow Mesenchymal Stem Cells

    ACS biomaterials science & engineering

More on Cellular senescence

Osteogenic differentiation

upin human cells1

1 study

  1. Tensile stress stimulation improves osteogenic differentiation in human cells.

    “The decline in osteogenic differentiation of aged JBMSCs was reversed by tensile stress stimulation.”

    Cellsin vitro 3D stress loading modeljaw bone marrow-derived mesenchymal stem cells

    Three-Dimensional Mechanical Microenvironment Rescued the Decline of Osteogenic Differentiation of Old Human Jaw Bone Marrow Mesenchymal Stem Cells

    ACS biomaterials science & engineering

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