Takinib

1 paper1 finding

1 lab in 1 country

Funder: Key Research and Development Program of Zhejiang Province

Animals1

Outcomes

1

Angiogenesis

downin human cells1

1 study

Takinib inhibits angiogenesis in human cells.
“the TAK1 inhibitors 5Z-7-oxozeaenol and takinib reversed the effects of conditioned media from senescent ARPE-19 cells on the wound healing, migration, survival, and tube formation abilities of HUVECs”
Cellsconditioned media from senescent ARPE-19 cells
Senescent retinal pigment epithelial cells promote angiogenesis in choroidal neovascularization via the TAK1/p38 MAPK pathway
Experimental eye research6 Jan 2025

More on Angiogenesis

Latest

1 in 12 months

Biogerontology28 Jul

AGGF1 delays endothelial cellular senescence through the TGFB3-TAK1-AMPK signaling axis

Experiments in human cellsAMPK signalling

Experimental Eye Research9 Jan

Senescent retinal pigment epithelial cells promote angiogenesis in choroidal neovascularization via the TAK1/p38 MAPK pathway

Experiments in ratsp38 MAPK signalling