Synthetic MIR-126 mimic oligonucleotide

Intervention

1 paper1 finding

  • 1 lab in 1 country
  • Funders: Comprehensive Cancer Center, City of Hope and 2 more
  • Animals1

Outcomes

1

Hematopoietic stem cell function

upin mice1

1 study
  1. Synthetic MIR-126 mimic oligonucleotide improves hematopoietic stem cell function in mice.

    “administration of a synthetic miR-126 mimic oligonucleotide restores EC-HSC communication and rescues aging-related HSC dysfunction”

    Animalsaging-related HSC dysfunctionbone marrow

    Loss of endothelial miR-126 drives age-related decline in hematopoiesis

    Haematologica4 Dec 2025

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