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Animals1

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1 in 12 months

Haematologica·4 Dec

Loss of endothelial miR-126 drives age-related decline in hematopoiesis

Experiments in miceBlood and immune system

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CD31+Sca-1high endothelial cells1
Inflammation1
LY6A1
MIR126A1
PECAM11
Stem cell differentiation1
Stem cell maintenance1
TNF-alpha1
Synthetic MIR-126 mimic oligonucleotide1

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Trials

AKG and Brain Health in AgingPhase 2Registered 6 Oct 2026, University of Oklahoma Safety and Preliminary Efficacy of Adipose-Derived Stem Cell Secretome in Frailty (VinVital)Phase 1Registered 2 Oct 2026, Vinmec Research Institute of Stem Cell and Gene Technology AI-Based Conversational Social Support for Older Adults With Heart FailureRegistered 7 Oct 2026, Chang Gung University of Science and Technology

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Topics

Mechanisms269 Interventions490 Biomarkers456 Populations648 AI & data176 Industry & policy25

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