AgingResearch.NewsJoin free

Spalax fibroblast conditioned medium

Spalax fibroblast conditioned medium has been studied in 1 paper since 2023: none in people yet, 1 in cells. No study of it in people or animals has been published yet. The newest paper, Mar 7, 2023: “Senescent Secretome of Blind Mole Rat Spalax Inhibits Malignant Behavior of Human Breast Cancer Cells Triggering Bystander Senescence and Targeting Inflammatory Response”.

Intervention

1 paper studies it3 findingsUpdated

None of its findings points the other way.

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funders: Israel Science Foundation and 1 more
  • Cells1

What did studies of Spalax fibroblast conditioned medium find?

3

Studies of Spalax fibroblast conditioned medium measured 3 outcomes; the most studied are cancer cell migration (1 study), inflammatory factor secretion (1) and cellular senescence (1).

Cancer cell migration

downin human cells1

1 study

  1. Spalax fibroblast conditioned medium decreases cancer cell migration in human cells.

    “Spalax CM suppressed the secretion of the main inflammatory factors in cancer cells and decreased their migration.”

    Cellshuman breast cancer cellsconditioned medium from senescent fibroblastsMDA-MB-231 and MCF-7

    Senescent Secretome of Blind Mole Rat Spalax Inhibits Malignant Behavior of Human Breast Cancer Cells Triggering Bystander Senescence and Targeting Inflammatory Response

    International journal of molecular sciences

Inflammatory factor secretion

downin human cells1

1 study

  1. Spalax fibroblast conditioned medium decreases inflammatory factor secretion in human cells.

    “Spalax CM suppressed the secretion of the main inflammatory factors in cancer cells”

    Cellshuman breast cancer cellsconditioned medium from senescent fibroblastsMDA-MB-231 and MCF-7

    Senescent Secretome of Blind Mole Rat Spalax Inhibits Malignant Behavior of Human Breast Cancer Cells Triggering Bystander Senescence and Targeting Inflammatory Response

    International journal of molecular sciences

Cellular senescence

upin human cells1

1 study

  1. Spalax fibroblast conditioned medium induces cellular senescence in human cells.

    “The results suggest that Spalax CM induced senescence in cancer cells”

    Cellshuman breast cancer cellsconditioned medium from senescent fibroblastsMDA-MB-231 and MCF-7

    Senescent Secretome of Blind Mole Rat Spalax Inhibits Malignant Behavior of Human Breast Cancer Cells Triggering Bystander Senescence and Targeting Inflammatory Response

    International journal of molecular sciences

More on Cellular senescence

Latest

Related