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Sleep restriction therapy

Intervention

2 papers6 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

  • 2 independent labs in 1 country
  • Funders: Alfred P. Sloan Foundation and others
  • Human trial1
  • Model organisms1

Outcomes

6

Reproductive fitness

upin flies1

1 study

  1. Sleep restriction therapy improves reproductive fitness in flies.

    “sleep impairments in these models are reversible with sleep restriction, with associated improvement in reproductive fitness and extended lifespan”

    Model organismsin aging and Alzheimer's disease fly models

    A Drosophila model of sleep restriction therapy for insomnia

    Molecular psychiatry1 Mar 2019

Lifespan

upin flies1

1 study

  1. Sleep restriction therapy extends lifespan in flies.

    “sleep impairments in these models are reversible with sleep restriction, with associated improvement in reproductive fitness and extended lifespan”

    Model organismsin aging and Alzheimer's disease fly models

    A Drosophila model of sleep restriction therapy for insomnia

    Molecular psychiatry1 Mar 2019

Sleep efficiency

upin flies1

1 study

  1. Sleep restriction therapy improves sleep efficiency in flies.

    “restriction of sleep opportunity through manipulation of environmental cues improves sleep efficiency in multiple short-sleeping Drosophila mutants”

    Model organismsin short-sleeping Drosophila mutants

    A Drosophila model of sleep restriction therapy for insomnia

    Molecular psychiatry1 Mar 2019

Daytime dysfunction

no changein humans1

1 study

  1. Sleep restriction therapy has no effect on daytime dysfunction in humans (1.94 vs 1.63, P = 0.272).

    “Mean of sleep medication intake and daytime dysfunction after intervention were 0.947, 1.94 in experimental group and 0.894, 1.63 in control group respectively, which showed no significant difference (P = 0.903, P = 0.272).”

    Human trial4 weekn = 38

    The effect of sleep restriction treatment on quality of sleep, sleep medication intake, and daytime function among the elderly who were members of Shiraz Jahandidegan canter in 2010

    Iranian journal of nursing and midwifery research1 Mar 2013

Sleep medication intake

no changein humans1

1 study

  1. Sleep restriction therapy has no effect on sleep medication intake in humans (0.947 vs 0.894, P = 0.903).

    “amount of sleep medication intake and daytime dysfunction did not show a significant difference after intervention.”

    Human trial4 weekn = 38

    The effect of sleep restriction treatment on quality of sleep, sleep medication intake, and daytime function among the elderly who were members of Shiraz Jahandidegan canter in 2010

    Iranian journal of nursing and midwifery research1 Mar 2013

Quality of sleep

upin humans1

1 study

  1. Sleep restriction therapy improves quality of sleep in humans (from 14.21 to 11.26 vs 13 to 12.78, P = 0.038).

    “Independent t-test showed a significant difference after the intervention (P = 0.038).”

    Human trial4 weekn = 38

    The effect of sleep restriction treatment on quality of sleep, sleep medication intake, and daytime function among the elderly who were members of Shiraz Jahandidegan canter in 2010

    Iranian journal of nursing and midwifery research1 Mar 2013

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