Sleep efficiency irregularity

Sleep efficiency irregularity has been studied in 2 papers since 2024: 2 observational studies in people; 1 in the past year. The newest paper, Nov 6, 2026: “Sleep Efficiency Irregularity Links PTSD with Early Cardiovascular Dysfunction in Young Adults”.

Exposure

2 papers study it3 findingsUpdated

1 new paper in 30 daysSee all 2 papers on sleep efficiency irregularity

At a glance

The findings reach people, from one lab or study. 2 independent labs in 2 countries.

“high irregularity (top quartile) in sleep efficiency (Ref: bottom quartile, HR: 1.35, 95% CI: 1.20, 1.53)”
DAYTIME ACTIVITY ATTENUATES ASSOCIATIONS BETWEEN SLEEP EFFICIENCY AND MORTALITY AMONG OLDER ADULTSGSA 2024 abstract2024doi:10.1093/geroni/igae098.4151

None of its findings points the other way.

Humans: a single group. Cells, worms or flies and mice: nothing yet.
  • 2 independent labs in 2 countries
  • Humans2

What is sleep efficiency irregularity linked with?

3

Studies link sleep efficiency irregularity with 3 measures: cardiovagal baroreflex sensitivity, oxidative stress and ROS signaling and mortality.

Cardiovagal baroreflex sensitivity

downin humans1

1 study
  1. Sleep efficiency irregularity is associated with cardiovagal baroreflex sensitivity in humans (PTSD).

    “Greater SE irregularity was significantly associated with higher oxidative stress and reduced cBRS in the PTSD group”

    HumansPTSD7 daysn = 28

    Sleep Efficiency Irregularity Links PTSD with Early Cardiovascular Dysfunction in Young Adults

    American journal of physiology. Regulatory, integrative and comparative physiology

More on Cardiovagal baroreflex sensitivity

Oxidative stress and ROS signaling

upin humans1

1 study
  1. Sleep efficiency irregularity is associated with oxidative stress and ROS signaling in humans (PTSD).

    “Greater SE irregularity was significantly associated with higher oxidative stress and reduced cBRS in the PTSD group”

    HumansPTSDwhole blood7 daysn = 28

    Sleep Efficiency Irregularity Links PTSD with Early Cardiovascular Dysfunction in Young Adults

    American journal of physiology. Regulatory, integrative and comparative physiology

More on Oxidative stress and ROS signaling

Mortality

upin humans1HR 1.35

1 study
  1. Sleep efficiency irregularity is linked with a higher risk of mortality in adjusted Cox models without daytime activity (HR: 1.35, 95% CI: 1.20, 1.53).

    “high irregularity (top quartile) in sleep efficiency (Ref: bottom quartile, HR: 1.35, 95% CI: 1.20, 1.53)”

    Humansin adjusted Cox models without daytime activity

    DAYTIME ACTIVITY ATTENUATES ASSOCIATIONS BETWEEN SLEEP EFFICIENCY AND MORTALITY AMONG OLDER ADULTS

    GSA 2024 abstract

Latest

Dec 2025: 0Jan 2026: 0Feb 2026: 0Mar 2026: 0Apr 2026: 0May 2026: 0Jun 2026: 0Jul 2026: 0Aug 2026: 0Sep 2026: 0Oct 2026: 0Nov 2026: 11 paper in 12 months