Sirtinol

2 papers1 finding

PubChem ChEBI MeSH

1 lab in 1 country

Funders: Deutsche Forschungsgemeinschaft and 1 more

Humans1
Cells1

Outcomes

1

ADIPOQ

downin human cells1

1 study

Sirtinol decreases ADIPOQ in human cells.
“The Sirt-1 inhibitor Sirtinol downregulated adiponectin protein expression and the number of adipocytes”
Cellsin ASCs
Oxidative stress and regulation of adipogenic differentiation capacity by sirtuins in adipose stem cells derived from female patients of advancing age
Scientific reportsAug 27, 2024

Latest

NeuropharmacologyApr 30

Sirtuins modulators mitigate hypoxia-induced cell death due to changes in histone 3 acetylation, and mitochondrial function, dynamics, and content

Experiments in rat cellsHypoxia and HIF signalling

Scientific ReportsAug 28

Oxidative stress and regulation of adipogenic differentiation capacity by sirtuins in adipose stem cells derived from female patients of advancing age

Study in peopleSirtuin signalling

International Journal of Molecular SciencesJun 10

The Role of Increased Expression of Sirtuin 6 in the Prevention of Premature Aging Pathomechanisms

ReviewMechanisms

Frontiers in EndocrinologyJan 26

Nicotinamide mononucleotide attenuates HIF-1α activation and fibrosis in hypoxic adipose tissue via NAD⁺/SIRT1 axis

Experiments in animalsInterventions

AntioxidantsJun 25

PPARδ Inhibits Hyperglycemia-Triggered Senescence of Retinal Pigment Epithelial Cells by Upregulating SIRT1

Experiments in cellsMechanisms

Oxidative Medicine and Cellular LongevityJan 29

Melatonin Improves the Resistance of Oxidative Stress-Induced Cellular Senescence in Osteoporotic Bone Marrow Mesenchymal Stem Cells

Experiments in animalsInterventions

Life SciencesMar 5

Nicotinamide mononucleotide attenuates isoproterenol-induced cardiac fibrosis by regulating oxidative stress and Smad3 acetylation

Experiments in animalsInterventions

International Journal of Medical SciencesMar 7

Hydrogen Sulfide Inhibits Homocysteine-Induced Neuronal Senescence by Up-Regulation of SIRT1

Experiments in cellsInterventions

BoneJan 25

Resveratrol inhibits adipocyte differentiation and cellular senescence of human bone marrow stromal stem cells

Experiments in cellsInterventions

Diabetes, Metabolic Syndrome and ObesityJan 1

DHA Protects Against Hepatic Steatosis by Activating Sirt1 in a High Fat Diet-Induced Nonalcoholic Fatty Liver Disease Mouse Model

Experiments in animalsInterventions