Severe dietary restriction

Severe dietary restriction extends lifespan in rats (nearly 50%).

“Our results show that a severe dietary restriction, excessive weight loss being prevented, paradoxically increased rat longevity by nearly 50%.”

Animalswith limited and controlled weight loss <=25%4 yearsmales

Paradoxical effect of severe dietary restriction on Long-Evans rat life span

International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition·1 Dec 2010