Senescent osteocyte-derived exosomes
Senescent osteocyte-derived exosomes has been studied in 1 paper since 2024: none in people yet, 1 in animals. The research so far is in animals. The newest paper, Feb 1, 2024: “Down-expression of miR-494-3p in senescent osteocyte-derived exosomes inhibits osteogenesis and accelerates age-related bone loss via PTEN/PI3K/AKT pathway”.
1 paper studies it1 findingUpdated
- 1 lab in 1 country
- Funders: Government of Jiangsu Province and 2 more
- Animals1
What did studies of Senescent osteocyte-derived exosomes find?
1Studies of Senescent osteocyte-derived exosomes measured 1 outcome; the most studied are bone loss (1 study).
Bone loss
upin mice1
1 study
Bone loss
upin mice1
Senescent osteocyte-derived exosomes increase bone loss in mice.
“In SAMP6 mice, senescent MLO-Y4 cell-derived exosomes accelerated bone loss, which was rescued by upregulation of exosomal miR-494-3p.”
Animalsin SAMP6 micebonemales
Bone & joint research