Senescence-associated t-cell transfer

Senescence-associated t-cell transfer induces liver fibrosis in mice.

“inducing severe hepatic steatosis and fibrosis at 36 weeks of age with an increase in OPN in the liver extract”

Animalstransplantation from 36-week-old NI spleen into 12-week-old NI spleenliver

Association Between CD4+/Programmed Cell Death 1+/CD153+ Cell Infiltration to the Aging Liver and Progression of Hepatic Steatosis in a Novel Metabolic Dysfunction-Associated Steatohepatitis Model Nishiura Mouse

Laboratory investigation; a journal of technical methods and pathology·13 Nov 2025

Senescence-associated t-cell transfer induces hepatic steatosis in mice.

“SA-T cells, but not CD4+/PD-1+/CD153- cells, prepared from 36-week-old spleens of NI mice were transplanted into 12-week-old spleens of NI mice, but not into those of B6 mice, inducing severe hepatic steatosis”

Animalstransplantation from 36-week-old NI spleen into 12-week-old NI spleenliver

Association Between CD4+/Programmed Cell Death 1+/CD153+ Cell Infiltration to the Aging Liver and Progression of Hepatic Steatosis in a Novel Metabolic Dysfunction-Associated Steatohepatitis Model Nishiura Mouse

Laboratory investigation; a journal of technical methods and pathology·13 Nov 2025