Selective nnmt inhibitor

Intervention

1 paper2 findings

  • 1 lab in 1 country
  • Funders: École Polytechnique Fédérale de Lausanne and 8 more
  • 2 of 2 findings with company ties
  • Humans1

Outcomes

2

Fibrosis

downin mice1

1 study
  1. Selective nnmt inhibitor decreases fibrosis in mice.

    “selective NNMT inhibition in senescent kidney cells, organoids, and in vivo is protective”

    Animalsin senescent kidney cells, organoids, and in vivo

    NNMT inhibition counteracts tubular senescence and fibrosis in early stages of chronic kidney disease

    Cell reports14 Jan 2026

Cellular senescence

downin mice1

1 study
  1. Selective nnmt inhibitor decreases cellular senescence in mice.

    “selective NNMT inhibition in senescent kidney cells, organoids, and in vivo is protective”

    Animalsin senescent kidney cells, organoids, and in vivo

    NNMT inhibition counteracts tubular senescence and fibrosis in early stages of chronic kidney disease

    Cell reports14 Jan 2026

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