Sclerostin inhibitors

Sclerostin inhibitors decrease alveolar bone loss.

“sclerostin inhibition demonstrates robust preclinical efficacy in rescuing bone loss in models of periodontitis and estrogen deficiency.”

Reviewin models of periodontitis and estrogen deficiency

The Role of Wnt Signaling in Age-Related Alveolar Bone Loss and Regeneration

Journal of periodontal research·4 Feb 2026