Scattered tubular-like cells

Scattered tubular-like cells has been studied in 2 papers since 2020: none in people yet, 2 in animals. The research so far is in animals. The newest paper, Jan 4, 2021: “Renovascular Disease Induces Senescence in Renal Scattered Tubular-Like Cells and Impairs Their Reparative Potency”.

Intervention

2 papers study it2 findingsUpdated

See all 2 papers on scattered tubular-like cells

At a glance

The findings reach mice, none yet in people. 1 lab in 1 country.

None of its findings points the other way.

Mice: a single group. Cells, worms or flies and humans: nothing yet.
  • 1 lab in 1 country
  • Funders: National Institute of Diabetes and Digestive and Kidney Diseases and 1 more
  • 2 of 2 findings with company ties
  • Animals2

What did studies of scattered tubular-like cells find?

2

Studies of scattered tubular-like cells measured 2 outcomes: profibrotic and inflammatory gene expression and glomerular filtration rate.

Profibrotic and inflammatory gene expression

downin mice1

1 study
  1. Scattered tubular-like cells decrease profibrotic and inflammatory gene expression in 2k,1c mice injected with healthy swine STCs.

    “downregulated profibrotic and inflammatory gene expression”

    Animalsin 2k,1c mice injected with healthy swine STCsfrom healthy swine kidneyskidney5×105 cells

    Renovascular Disease Induces Senescence in Renal Scattered Tubular-Like Cells and Impairs Their Reparative Potency

    Hypertension (Dallas, Tex. : 1979)

More on Profibrotic and inflammatory gene expression

Glomerular filtration rate

upin mice1

1 study
  1. Scattered tubular-like cells improve glomerular filtration rate in 2k,1c mice injected with healthy swine STCs.

    “Delivery of normal pig STCs in 2k,1c mice improved murine renal perfusion, blood flow, and glomerular filtration rate, and downregulated profibrotic and inflammatory gene expression.”

    Animalsin 2k,1c mice injected with healthy swine STCsfrom healthy swine kidneyskidney5×105 cells

    Renovascular Disease Induces Senescence in Renal Scattered Tubular-Like Cells and Impairs Their Reparative Potency

    Hypertension (Dallas, Tex. : 1979)

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