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Retroviral vector LXSN-16E6E7

Intervention

1 paper1 finding

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funders: Academia Sinica and 1 more
  • Cells1

Outcomes

1

Replicative lifespan

upin human cells1

1 study

  1. Retroviral vector LXSN-16E6E7 increases replicative lifespan in human cells (beyond 100 PDs vs 30 PDs).

    “Whereas parental hMSCs ceased to grow after 30 PDs, KP-hMSCs could be propagated beyond 100 PDs.”

    Cellsretroviral vector LXSN-16E6E7 transduction

    Immortalization without neoplastic transformation of human mesenchymal stem cells by transduction with HPV16 E6/E7 genes

    International journal of cancer20 Jun 2004

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