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Reg3γ

Reg3γ has been studied in 1 paper since 2026: none in people yet, 1 in animals; 1 in the past year. The research so far is in animals. The newest story, Oct 26, 2026: “Protein loss made irregular rhythms harder to trigger in mice”.

Intervention

1 paper studies it2 findingsUpdated

1 new paper in 30 daysSee all 1 papers on reg3γ

At a glance

The findings reach cells, none yet in people. 1 lab in 1 country.

None of its findings points the other way.

Cells: a single group. Worms or flies, mice and humans: nothing yet.

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funder: National Natural Science Foundation of China
  • Animals1

What did studies of reg3γ find?

2

Studies of reg3γ measured 2 outcomes: CCL17 and macrophage activation.

CCL17

upin cells1

1 study

  1. Reg3γ increases CCL17 in cells.

    “RNA sequencing of recombinant Reg3γ-treated bone marrow-derived macrophages (BMDMs) revealed significant upregulation of CCL17”

    Cellsrecombinantbone marrow-derived macrophage

    Protein loss made irregular rhythms harder to trigger in mice

    ESC Congress 2026 abstract

More on CCL17

macrophage activation

upin cells1

1 study

  1. Reg3γ induces macrophage activation in cells.

    “in vitro experiments demonstrated that Reg3γ recruits and activates macrophages by directly binding to gp130”

    Cellsmacrophage

    Protein loss made irregular rhythms harder to trigger in mice

    ESC Congress 2026 abstract

Latest

Dec 2025: 0Jan 2026: 0Feb 2026: 0Mar 2026: 0Apr 2026: 0May 2026: 0Jun 2026: 0Jul 2026: 0Aug 2026: 0Sep 2026: 0Oct 2026: 1Nov 2026: 01 paper in 12 months
ESC Congress 2026 Abstract

Protein loss made irregular rhythms harder to trigger in mice

Aging mice lacking the protein in heart muscle cells had reduced structural changes in the heart’s upper chambers and lower susceptibility to an experimentally triggered…Aging mice lacking the protein in heart muscle cells had reduced structural changes in the heart’s upper chambers and lower susceptibility to an experimentally triggered irregular heartbeat.

Mouse studyMechanisms
Paper

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