Reecap

Reecap increases locus discovery in silico (178 loci (27 colocalized, 14 novel)).

“GWAS of REECAP embeddings identifies 178 loci, including 27 that colocalize with risk loci of age-related eye diseases, 14 of which remained undetected by conventional disease-label GWAS.”

In silicoretinan = 52,742

REECAP: Contrastive learning of retinal aging reveals genetic loci linking morphology to eye disease

medRxiv : the preprint server for health sciences·27 Nov 2025Preprint