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Recombinant human grancalcin

Intervention

1 paper1 finding

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funders: Chinese University of Hong Kong and 2 more
  • Animals1

Outcomes

1

Fracture repair

downin mice1

1 study

  1. Recombinant human grancalcin impairs fracture repair in mice.

    “Local injection of human rGCA in young mice induced SSPC senescence and delayed fracture repair.”

    Animalsfracture healing in young mice

    Age-related secretion of grancalcin by macrophages induces skeletal stem/progenitor cell senescence during fracture healing

    Bone research25 Jan 2024

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