Recombinant herpes zoster vaccine

1. Recombinant herpes zoster vaccine lowers the risk of atrial fibrillation in humans (7% decrease, RMTL ratio = 0.93 (95% CI 0.88-0.98)).

   Humans

   Recombinant shingles vaccination and the risk of cardiovascular events · Nature medicine · 26 Aug 2026

Atrial fibrillation →

1. Recombinant herpes zoster vaccine lowers the risk of ischemic stroke in humans (12% decrease, RMTL ratio = 0.88 (95% CI 0.78-0.98)).

   Humansmales

   Recombinant shingles vaccination and the risk of cardiovascular events · Nature medicine · 26 Aug 2026

Ischemic stroke →

1. Recombinant herpes zoster vaccine lowers the risk of heart failure in humans (12% decrease, RMTL ratio = 0.88 (95% CI 0.83-0.93)).

   Humans

   Recombinant shingles vaccination and the risk of cardiovascular events · Nature medicine · 26 Aug 2026

Heart failure →

1. Recombinant herpes zoster vaccine lowers the risk of ischemic heart disease in humans (10% decrease, RMTL ratio = 0.90 (95% CI 0.87-0.94)).

   Humans

   Recombinant shingles vaccination and the risk of cardiovascular events · Nature medicine · 26 Aug 2026

Ischemic heart disease →

1. Recombinant herpes zoster vaccine lowers the risk of cardiovascular disease in humans (9% decrease, RMTL ratio = 0.91 (95% CI 0.88-0.95)).

   Humans7 years

   Recombinant shingles vaccination and the risk of cardiovascular events · Nature medicine · 26 Aug 2026

Cardiovascular disease →