Rat adipose stem cells + SPHINGOSINE-1-PHOSPHATE

Rat adipose stem cells + SPHINGOSINE-1-PHOSPHATE increases vascular graft patency in rats (90% versus 66% with rASC/dHUA and 60% with dHUA; not significant versus rASC/dHUA).

“The rASC/S1P/dHUA group exhibited a better patency rate of 90% after 90 days of implantation compared to 66% and 60% observed in the rASC/dHUA and dHUA groups, respectively.”

Animalscompared with rASC-recellularized and non-recellularized scaffoldsrASC/S1P-recellularized decellularized human umbilical artery scaffoldabdominal aorta90 days

Biological modification of decellularized human umbilical artery with adipose stem cells and sphingosine-1-phosphate for development of thromboresistant small caliber vascular graft

Stem cell research & therapy·14 Oct 2026