Propylpyrazole triol

Intervention

1 paper3 findings

  • 1 lab in 1 country
  • Funder: National Natural Science Foundation of China
  • Animals1

Outcomes

3

Cognitive function

upin mice1

1 study
  1. Propylpyrazole triol improves cognitive function in mice.

    “Erα activation with PPT suppressed PTEN nuclear translocation, preserved synaptic structure, and improved cognitive function”

    AnimalsRepeated sevoflurane exposurefemales

    ERα Agonist Protects Aged Female Mice From Sevoflurane Neurotoxicity via PTEN Nuclear Translocation

    CNS neuroscience & therapeutics29 May 2026

Synaptic structure

downin mice1

1 study
  1. Propylpyrazole triol protects against synaptic structure in mice.

    “Erα activation with PPT suppressed PTEN nuclear translocation, preserved synaptic structure, and improved cognitive function”

    AnimalsRepeated sevoflurane exposurehippocampusfemales

    ERα Agonist Protects Aged Female Mice From Sevoflurane Neurotoxicity via PTEN Nuclear Translocation

    CNS neuroscience & therapeutics29 May 2026

PTEN nuclear translocation

downin mice1

1 study
  1. Propylpyrazole triol inhibits PTEN nuclear translocation in mice.

    “Erα activation with PPT suppressed PTEN nuclear translocation”

    AnimalsRepeated sevoflurane exposurehippocampusfemales

    ERα Agonist Protects Aged Female Mice From Sevoflurane Neurotoxicity via PTEN Nuclear Translocation

    CNS neuroscience & therapeutics29 May 2026

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