Synaptophysin

1 paper2 findings

Animals1

Interventions

2

Young blood plasma

upin mice1

1 study

Young blood plasma increases synaptophysin in mice (P < .001).
“following intravenous plasma administration (synaptophysin P < .001; calbindin P = .14)”
Animalsin aged mutant amyloid precursor protein micehippocampus
Preclinical Assessment of Young Blood Plasma for Alzheimer Disease
JAMA neurology1 Nov 2016

More on Young blood plasma

Heterochronic parabiosis

upin mice1

1 study

Heterochronic parabiosis increases synaptophysin in mice (P = .02).
“showed a near complete restoration in levels of synaptic and neuronal proteins after exposure to young blood in parabiosis (synaptophysin P = .02; calbindin P = .02)”
Animalsin aged mutant amyloid precursor protein micehippocampus
Preclinical Assessment of Young Blood Plasma for Alzheimer Disease
JAMA neurology1 Nov 2016

More on Heterochronic parabiosis

Latest

4 in 12 months

Chinese Journal of Gerontology15 h

Effects and mechanisms of action of hUMSCs-Exos on sevoflurane-induced postoperative cognitive dysfunction and synaptic plasticity impairment in aged mice

Experiments in 10 miceInterventions

Journal of Visualized Experiments9 Sep

Effects of Qi-fu-yin on Improving Cognitive Impairment and Reducing Cellular Senescence in the Brains of 5xFAD Mice

Experiments in miceMild cognitive impairment

Neurochemical Research21 Aug

CT1812 Attenuates Surgery-Induced Cognitive Impairment and Modulates TMEM97- and PGRMC1-Associated Hippocampal Stress Responses in Aged Mice

Experiments in miceInterventions

AAIC 2025 Abstract24 Dec

Therapeutic Potential of Dehydroepiandrosterone in Reversing Age‐Related Neurodegenerative and Cognitive Declines in Rats

Experiments in ratsInterventions

JAMA Neurology1 Nov

Preclinical Assessment of Young Blood Plasma for Alzheimer Disease

Experiments in miceAlzheimer's disease