PRDX3 gene therapy

Intervention

1 paper4 findings

  • 1 lab in 1 country
  • Animals1

Outcomes

4

Cognitive function

upin mice1

1 study
  1. PRDX3 gene therapy improves cognitive function in mice.

    “The mRVG9R-PRDX3 gene therapy improved motor and cognitive functions in the PD animal model”

    AnimalsParaquat-induced Parkinson's disease model in C57BL/6 micemRVG9R-PRDX3 complexmales

    Antioxidant PRDX3 gene therapy protects brain cells and prevents neurodegeneration in an animal model of Parkinson's disease

    Neuropeptides27 Dec 2024

Motor function

upin mice1

1 study
  1. PRDX3 gene therapy improves motor function in mice.

    “The mRVG9R-PRDX3 gene therapy improved motor and cognitive functions in the PD animal model”

    AnimalsParaquat-induced Parkinson's disease model in C57BL/6 micemRVG9R-PRDX3 complexmales

    Antioxidant PRDX3 gene therapy protects brain cells and prevents neurodegeneration in an animal model of Parkinson's disease

    Neuropeptides27 Dec 2024

Cellular senescence

downin mice1

1 study
  1. PRDX3 gene therapy prevents cellular senescence in mice.

    “Animals treated with the mRVG9R-PRDX3 complex showed a clear reduction in PQ-induced PD symptomatology and prevented cellular senescence in the substantia nigra's neuronal population.”

    AnimalsParaquat-induced Parkinson's disease model in C57BL/6 micemRVG9R-PRDX3 complexsubstantia nigra neuronsmales

    Antioxidant PRDX3 gene therapy protects brain cells and prevents neurodegeneration in an animal model of Parkinson's disease

    Neuropeptides27 Dec 2024

More on Cellular senescence

Parkinson's disease symptoms

downin mice1

1 study
  1. PRDX3 gene therapy decreases parkinson's disease symptoms in mice.

    “Animals treated with the mRVG9R-PRDX3 complex showed a clear reduction in PQ-induced PD symptomatology”

    AnimalsParaquat-induced Parkinson's disease model in C57BL/6 micemRVG9R-PRDX3 complexmales

    Antioxidant PRDX3 gene therapy protects brain cells and prevents neurodegeneration in an animal model of Parkinson's disease

    Neuropeptides27 Dec 2024

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