Pralatrexate

Pralatrexate has been studied in 1 paper since 2026: none in people yet, 1 in cells; 1 in the past year. No study of it in people or animals has been published yet. The newest story, Nov 9, 2026: “Gene activity clock tracks relative age across human tissues”.

Intervention

1 paper studies it1 findingUpdated

PubChemChEBI

See all 1 papers on pralatrexate

At a glance

The findings reach cells, none yet in people. 1 lab in 1 country; 15 trials, none about aging, 4 with no results posted.

Cells: a single group. Worms or flies, mice and humans: nothing yet.
  • 1 lab in 1 country
  • 15 trials, none about aging, 4 with no results posted
  • Funders: AstraZeneca and 8 more
  • Cells1

What did studies of pralatrexate find?

1

Studies of pralatrexate measured one outcome, cellular senescence.

Cellular senescence

upin human cells1

1 study
  1. Pralatrexate induces cellular senescence in human cells.

    “Experimental validation confirmed pralatrexate as a potent senescence inducer”

    Cellsin human cells

    Gene activity clock tracks relative age across human tissues

    Advanced science (Weinheim, Baden-Wurttemberg, Germany)

More on Cellular senescence

Who is developing pralatrexate?

1 company: Acrotech Biopharma.

Companies
  • Acrotech BiopharmaPhase 3peripheral t cell lymphoma

Trial sponsors

Latest

Dec 2025: 0Jan 2026: 0Feb 2026: 0Mar 2026: 0Apr 2026: 0May 2026: 0Jun 2026: 0Jul 2026: 1Aug 2026: 0Sep 2026: 0Oct 2026: 0Nov 2026: 01 paper in 12 months
Advanced Science

Gene activity clock tracks relative age across human tissues

Trained on 17,212 healthy-donor samples, the model predicted relative age across tissues and several methods of measuring gene activity.Trained on 17,212 healthy-donor samples, the model predicted relative age across tissues and several methods of measuring gene activity.

Computational studyBiomarkers