Polyphenol-rich plant extract

Intervention

1 paper4 findings

  • 1 lab in 1 country
  • Funders: Agence Nationale de la Recherche and 2 more
  • 4 of 4 findings with company ties
  • Animals1

Outcomes

4

Cholesterol accumulation

downin mice1

1 study
  1. Polyphenol-rich plant extract decreases cholesterol accumulation in mice.

    “reduces adipose accumulation of cholesterol and cholesterol oxides”

    Animalsin obese mice fed a high-fat/high-sucrose dietadipose tissue

    Healthy adiposity and extended lifespan in obese mice fed a diet supplemented with a polyphenol-rich plant extract

    Scientific reports24 Jun 2019

More on Cholesterol accumulation

Endotoxaemia

downin mice1

1 study
  1. Polyphenol-rich plant extract decreases endotoxaemia in mice.

    “improves plasma lipid levels and endotoxaemia”

    Animalsin obese mice fed a high-fat/high-sucrose diet

    Healthy adiposity and extended lifespan in obese mice fed a diet supplemented with a polyphenol-rich plant extract

    Scientific reports24 Jun 2019

More on Endotoxaemia

Macrophage recruitment

downin mice1

1 study
  1. Polyphenol-rich plant extract prevents macrophage recruitment in mice.

    “prevents macrophage recruitment to adipose tissues”

    Animalsin obese mice fed a high-fat/high-sucrose dietadipose tissue

    Healthy adiposity and extended lifespan in obese mice fed a diet supplemented with a polyphenol-rich plant extract

    Scientific reports24 Jun 2019

More on Macrophage recruitment

Lifespan

upin mice1

1 study
  1. Polyphenol-rich plant extract extends lifespan in mice.

    “supplementation with a polyphenol-rich plant extract (PRPE) improves plasma lipid levels and endotoxaemia, prevents macrophage recruitment to adipose tissues, reduces adipose accumulation of cholesterol and cholesterol oxides, and extends the median lifespan.”

    Animalsin obese mice fed a high-fat/high-sucrose diet

    Healthy adiposity and extended lifespan in obese mice fed a diet supplemented with a polyphenol-rich plant extract

    Scientific reports24 Jun 2019

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