PMX205

1 paper1 finding

1 lab in 1 country

Funders: Beijing Municipal Science and Technology Commission and 2 more

Humans1

Outcomes

1

Spatial memory

upin mice1

1 study

PMX205 improves spatial memory in mice.
“subsequent spatial memory decline were attenuated following treatment with the specific C5aR1 antagonist PMX205 in senescence-accelerated (SAMP8) mice”
Animalsin senescence-accelerated (SAMP8) micehippocampus
Hippocampal C5a-C5aR1 axis drives age-related memory decline via collapsing synaptic chloride homeostasis
Brain, behavior, and immunity1 Jul 2026

Latest

1 in 12 months

Brain, Behavior, and Immunity2 Jul

Hippocampal C5a-C5aR1 axis drives age-related memory decline via collapsing synaptic chloride homeostasis

Study in peopleSynapse