Plasma exosomes

Plasma exosomes has been studied in 3 papers since 2019: none in people yet, 2 in animals, 1 in cells; 1 in the past year. The research so far is in animals and cells. The newest story, Nov 9, 2026: “Blood particles from active rats change gene activity in older rats”.

Intervention

3 papers study it1 findingUpdated

See all 3 papers on plasma exosomes

At a glance

The findings reach cells, none yet in people. 1 lab in 1 country.

Cells: a single group. Worms or flies, mice and humans: nothing yet.
  • 1 lab in 1 country
  • Funders: National Heart, Lung, and Blood Institute and 2 more
  • Animals2
  • Cells1

What did studies of plasma exosomes find?

1

Studies of plasma exosomes measured one outcome, SIRT6.

SIRT6

downin human cells1

1 study
  1. Plasma exosomes decrease SIRT6 in endothelial cells exposed to OSA plasma exosomes (p < 0.009).

    “SIRT1 and SIRT6 expression levels were decreased (p < 0.02 and p < 0.009)”

    Cellsin endothelial cells exposed to OSA plasma exosomesplasma-derivedendothelial cellsn = 15

    Plasma exosomes in OSA patients promote endothelial senescence: effect of long-term adherent continuous positive airway pressure

    Sleep

More on SIRT6

Funding

1 grant since 2018

National Institute of Allergy and Infectious Diseases$423K

Latest

Dec 2025: 0Jan 2026: 0Feb 2026: 0Mar 2026: 0Apr 2026: 0May 2026: 1Jun 2026: 0Jul 2026: 0Aug 2026: 0Sep 2026: 0Oct 2026: 0Nov 2026: 01 paper in 12 months
Frontiers in Aging Neuroscience

Blood particles from active rats change gene activity in older rats

Nine sedentary male rats received brain infusions for seven days; particles from exercised donors prompted molecular changes consistent with exercise adaptations.Nine sedentary male rats received brain infusions for seven days; particles from exercised donors prompted molecular changes consistent with exercise adaptations.

Rat studyInterventions