Plant-protein replacement diet

Intervention

1 paper4 findings

  • 1 lab in 1 country
  • Human trial1

Outcomes

4

Plasma glucuronidated bile acids

upin humans1

1 study
  1. Plant-protein replacement diet increases plasma glucuronidated bile acids in humans.

    “Plasma glucuronidated BAs increased, expanding the circulating pool of readily excreted BA conjugates.”

    Human trialhealthy adults12 weeksn = 136

    Replacing animal-sourced with plant-sourced proteins alters gut microbiota and biomarkers associated with colorectal cancer risk in healthy adults: A randomized feeding study

    medRxiv14 Oct 2026Preprint

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Fecal secondary and taurine-conjugated bile acids

downin humans1

1 study
  1. Plant-protein replacement diet decreases fecal secondary and taurine-conjugated bile acids in humans.

    “The 70% plant-protein diet also reduced fecal secondary and taurine-conjugated BAs, including the CRC-associated BAs DCA and LCA.”

    Human trialhealthy adults70% of protein from plant sources12 weeksn = 136

    Replacing animal-sourced with plant-sourced proteins alters gut microbiota and biomarkers associated with colorectal cancer risk in healthy adults: A randomized feeding study

    medRxiv14 Oct 2026Preprint

More on Fecal secondary and taurine-conjugated bile acids

Fecal total and haem-derived N-nitroso compounds

downin humans1

1 study
  1. Plant-protein replacement diet decreases fecal total and haem-derived N-nitroso compounds in humans.

    “potentially carcinogenic total and haem-derived NOCs declined progressively with plant-protein replacement.”

    Human trialhealthy adults30%, 50%, or 70% of protein from plant sources12 weeksn = 136

    Replacing animal-sourced with plant-sourced proteins alters gut microbiota and biomarkers associated with colorectal cancer risk in healthy adults: A randomized feeding study

    medRxiv14 Oct 2026Preprint

More on Fecal total and haem-derived N-nitroso compounds

Gut microbiota composition

upin humans1

1 study
  1. Plant-protein replacement diet increases gut microbiota composition in humans.

    “The 70% plant-protein diet significantly restructured the gut microbiota, increasing fiber-associated Lachnospiraceae and Roseburia while reducing Methanobrevibacter and several asaccharolytic taxa.”

    Human trialhealthy adults70% of protein from plant sources12 weeksn = 136

    Replacing animal-sourced with plant-sourced proteins alters gut microbiota and biomarkers associated with colorectal cancer risk in healthy adults: A randomized feeding study

    medRxiv14 Oct 2026Preprint

More on Gut microbiota composition

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