Particulate manganese ≤2.5 μm
Intervention1 paper2 findings
C · W · M · H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.
Labs are independent when their papers share no last author and no institution.
Against: findings that point the other way from most findings on the same outcome.
No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.
Company ties: findings with an author at a company, or from a paper that declares the maker’s interest.
- Humans1
Associations
2pTau-181/Aβ42 ratio
upin humans1
1 study
pTau-181/Aβ42 ratio
upin humans1
Particulate manganese ≤2.5 μm is associated with pTau-181/Aβ42 ratio in humans (β = 0.057, 95% CI 0.005 to 0.108).
Humanscognitively unimpairedplasmaper interquartile-range increasen = 340
Air pollution particles link to distinct Alzheimer's markers · Environmental pollution (Barking, Essex : 1987) · 7 Oct 2026
pTau-181
upin humans1
1 study
pTau-181
upin humans1
Particulate manganese ≤2.5 μm is associated with pTau-181 in humans (β = 0.387, 95% CI 0.084 to 0.691).
Humanscognitively unimpairedplasmaper interquartile-range increasen = 340
Air pollution particles link to distinct Alzheimer's markers · Environmental pollution (Barking, Essex : 1987) · 7 Oct 2026
Latest
1Air pollution particles link to distinct Alzheimer's markers
In 340 unimpaired adults, fine particles were linked to lower amyloid ratios while particulate manganese was linked to higher levels of tau.In 340 unimpaired adults, fine particles were linked to lower amyloid ratios while particulate manganese was linked to higher levels of tau.