P12C5

1 paper2 findings

1 lab in 1 country

Funders: Basic and Applied Basic Research Foundation of Guangdong Province and 3 more

Human trial1

Outcomes

2

Inflammation

downin mice1

1 study

P12C5 decreases inflammation in mice.
“reversed the pro-inflammatory immunometabolic phenotype in testicular macrophages”
Animalstestis
Targeting the CMKLR1-Mediated Signaling Rebalances Immunometabolism State in Middle-Age Testicular Macrophages
Advanced science (Weinheim, Baden-Wurttemberg, Germany)15 Jan 2026

More on Inflammation

Spermatogenesis

upin mice1

1 study

P12C5 improves spermatogenesis in mice.
“Systemic administration of a newly developed CMKLR1 antagonist peptide (P12C5) or non-pharmacological intervention such as high-intensity interval training (HIIT) rescued spermatogenesis”
Animals
Targeting the CMKLR1-Mediated Signaling Rebalances Immunometabolism State in Middle-Age Testicular Macrophages
Advanced science (Weinheim, Baden-Wurttemberg, Germany)15 Jan 2026

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Advanced Science15 Jan

Targeting the CMKLR1-Mediated Signaling Rebalances Immunometabolism State in Middle-Age Testicular Macrophages

Trial in peopleInterventions