Overtraining

Intervention

2 papers4 findings

  • 2 independent labs in 2 countries
  • Funders: Conselho Nacional de Desenvolvimento Científico e Tecnológico and 4 more
  • Animals2

Outcomes

4

Physical function

downin mice1

1 study
  1. Overtraining impairs physical function in mice.

    “the overtrained group presented higher expression of Sqstm1 and Bnip3 with negative morphological and physical performance adaptations for the liver and heart, respectively.”

    Animalsovertrainingheart

    Moderate, but Not Excessive, Training Attenuates Autophagy Machinery in Metabolic Tissues

    International journal of molecular sciencesNov 10, 2020

BNIP3

upin mice1

1 study
  1. Overtraining increases BNIP3 in mice.

    “the overtrained group presented higher expression of Sqstm1 and Bnip3 with negative morphological and physical performance adaptations for the liver and heart, respectively.”

    Animalsovertrainingliver

    Moderate, but Not Excessive, Training Attenuates Autophagy Machinery in Metabolic Tissues

    International journal of molecular sciencesNov 10, 2020

More on BNIP3

SQSTM1

upin mice1

1 study
  1. Overtraining increases SQSTM1 in mice.

    “the overtrained group presented higher expression of Sqstm1 and Bnip3 with negative morphological and physical performance adaptations for the liver and heart, respectively.”

    Animalsovertrainingliver

    Moderate, but Not Excessive, Training Attenuates Autophagy Machinery in Metabolic Tissues

    International journal of molecular sciencesNov 10, 2020

More on SQSTM1

Long-term memory processing

no changein mice1

1 study
  1. Overtraining has no effect on long-term memory processing in mice.

    “practicing the avoidance response (overtraining) did not alleviate the impairment of long-term memory processing.”

    Animalsovertraining

    Age-related changes in footshock avoidance acquisition and retention in senescence accelerated mouse (SAM)

    Neurobiology of agingJan 1, 1993

Latest