Osteogenic growth peptide

1. Osteogenic growth peptide inhibits myofibroblast proliferation in mouse cells.

   “OGP inhibits myofibroblast proliferation in murine primary cell cultures.”

   Cellsin murine primary cell cultures

   Therapeutic potential of cannabinoid receptor 2 agonist osteogenic growth peptide in lung fibrosis in aged mice

   American journal of respiratory cell and molecular biology·May 6, 2026

1. Osteogenic growth peptide decreases myofibroblast activation in mice.

   “demonstrated a significant anti-fibrotic effect of OGP and its ability to mitigate myofibroblast activation in vivo.”

   Animalsin young and aged bleomycin-treated mice

   Therapeutic potential of cannabinoid receptor 2 agonist osteogenic growth peptide in lung fibrosis in aged mice

   American journal of respiratory cell and molecular biology·May 6, 2026

1. Osteogenic growth peptide decreases pulmonary fibrosis in mice.

   “Histologically, OGP treatment significantly reduced the Ashcroft scale of disease severity, collagen content, and extracellular matrix (ECM) thickening in young and aged BLM-treated mice.”

   Animalsin young and aged bleomycin-treated mice

   Therapeutic potential of cannabinoid receptor 2 agonist osteogenic growth peptide in lung fibrosis in aged mice

   American journal of respiratory cell and molecular biology·May 6, 2026

More on Pulmonary fibrosis

1. Osteogenic growth peptide improves survival in mice.

   “OGP significantly improved survival and reduced weight loss in BLM-treated mice.”

   Animalsin bleomycin-induced lung fibrosis

   Therapeutic potential of cannabinoid receptor 2 agonist osteogenic growth peptide in lung fibrosis in aged mice

   American journal of respiratory cell and molecular biology·May 6, 2026