Osk mrna
1 paper3 findings
- 1 lab in 1 country
- Funders: Ministry of Science and Technology of the People's Republic of China and 4 more
- Animals1
Outcomes
3TGFB1
downin mice1
1 study
TGFB1
downin mice1
Osk mrna decreases TGFB1 in mice.
“downregulates fibrogenic mediators (Tgfb1, Pdgfb)”
Animalsin a CCl4-induced liver fibrosis mouse modelliver
Journal of controlled release : official journal of the Controlled Release SocietyDec 22, 2025
Extracellular matrix remodelling
downin mice1
1 study
Extracellular matrix remodelling
downin mice1
Osk mrna inhibits extracellular matrix remodelling in mice.
“halting extracellular matrix (ECM) deposition”
Animalsin a CCl4-induced liver fibrosis mouse modelliver
Journal of controlled release : official journal of the Controlled Release SocietyDec 22, 2025
Liver fibrosis
downin mice1
1 study
Liver fibrosis
downin mice1
Osk mrna decreases liver fibrosis in mice.
“Hepatocyte-specific partial cellular reprogramming via selective OSK mRNA lipid nanoparticle attenuates liver fibrosis”
Animalsin a CCl4-induced liver fibrosis mouse modelliver
Journal of controlled release : official journal of the Controlled Release SocietyDec 22, 2025
Latest
1 in 12 monthsJournal of Controlled Release
Hepatocyte-specific partial cellular reprogramming via selective OSK mRNA lipid nanoparticle attenuates liver fibrosis
Experiments in miceLiver fibrosis