Ortho-vanillin

1. Ortho-vanillin decreases islet fibrosis in mice.

   Animalspancreas60 mg/kg bodyweight4 months

   Toll-like receptor 2 modulates age-associated insulitis and fibrotic remodeling of Langerhans islets · Immunity & ageing : I & A · 12 Sep 2026

1. Ortho-vanillin decreases insulitis in mice.

   Animalspancreas60 mg/kg bodyweight4 months

   Toll-like receptor 2 modulates age-associated insulitis and fibrotic remodeling of Langerhans islets · Immunity & ageing : I & A · 12 Sep 2026

1. Ortho-vanillin decreases cellular senescence in human cells.

   Cellsin induced senescent outer annulus fibrosus cellsouter annulus fibrosus cell

   A Standardized In Vitro Platform for Senolytic Drug Discovery in Human Musculoskeletal Cells · bioRxiv · 21 Aug 2026 · Preprint

Cellular senescence →