Organochlorine pesticides

Exposure

4 papers2 findings

  • 2 independent labs in 2 countries
  • Funders: Svenska Forskningsrådet Formas and 1 more
  • Humans4

Associations

2

NfL

upin humans1

1 study
  1. Organochlorine pesticides are associated with NfL in humans (beta=0.33 (0.17, 0.49)).

    “Among males, OCP was associated with increased NfL (2nd vs. 1st tertile: beta=0.33 (0.17, 0.49)); p-interaction sex*OCP <0.001).”

    Humans2nd vs. 1st tertileplasma7-year follow-upmalesn = 1,837

    Persistent Organic Pollutants and Plasma Markers of Neurodegeneration in SOL-INCA and HCHS/SOL

    GSA 2025 abstract31 Dec 2025

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Stroke

upin humans1OR 4

1 study
  1. Organochlorine pesticides raise the risk of stroke in humans (OR 4.0, 95% CI 1.1-14.6).

    “4.0 (1.1-14.6) for OC pesticides; corresponding ORs for those ≥ 95th percentile were 7.8 (2.1-29.6) and 9.5 (2.3-38.9).”

    Humans5 yearsn = 898

    Background exposure to persistent organic pollutants predicts stroke in the elderly

    Environment international17 Jul 2012

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