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Oleacin

Intervention

1 paper studies it2 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funder: Ministero dell'Università e della Ricerca
  • Cells1

Outcomes

1

Inflammation

downin human cells1

1 study

  1. Oleacin decreases inflammation in human cells.

    “Results showed that OC and OA are efficient in ameliorating almost all of the pro-inflammatory readouts (IL-1β, TNF-α, IL-8, ICAM, VCAM) and reducing the release of IL-6”

    Cellsin LPS-treated THP-1 and HUVECs, senescent HUVECs, and Poly(I:C)-treated hSAECs

    Anti-Inflammatory Effects of Olive Leaf Extract and Its Bioactive Compounds Oleacin and Oleuropein-Aglycone on Senescent Endothelial and Small Airway Epithelial Cells

    Antioxidants (Basel, Switzerland)Jul 28, 2023

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Associations

1

ACE2

mixedin human cells1

1 study

  1. Oleacin is associated with ACE2 in human cells.

    “In hSAECs, they also modulate the expression of SOD2, NF-kB and also ACE2 and TMPRSS2”

    Cellssmall airway epithelial cells

    Anti-Inflammatory Effects of Olive Leaf Extract and Its Bioactive Compounds Oleacin and Oleuropein-Aglycone on Senescent Endothelial and Small Airway Epithelial Cells

    Antioxidants (Basel, Switzerland)Jul 28, 2023

More on ACE2

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