Obese plasma

1. Obese plasma increases CDKN2A in mice (log10-fold change: 1.48).

   “In eWAT, p16 expression was significantly elevated (P = 0.019; log10-fold change: 1.48).”

   Animalscompared to non-obese plasma transferepididymal white adipose tissue150 μl once weekly4 weeks

   Obese plasma transfer accelerates cellular aging in the C57BL/6 mouse model

   Immunity & ageing : I & A·29 Dec 2025

More on CDKN2A

1. Obese plasma increases senescence-associated beta-galactosidase in mice.

   “Mice in the PO group showed significantly increased SA-β-gal activity in eWAT (P < 0.05) and PBMCs (P < 0.001) compared to the PNO group.”

   Animalscompared to non-obese plasma transferepididymal white adipose tissue150 μl once weekly4 weeks

   Obese plasma transfer accelerates cellular aging in the C57BL/6 mouse model

   Immunity & ageing : I & A·29 Dec 2025

More on Senescence-associated beta-galactosidase