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Nutrient restriction

Exposure

1 paper2 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Humans1

Outcomes

2

Cognitive-affective symptoms

upin humans1

1 study

  1. Nutrient restriction increases cognitive-affective symptoms in humans (+0.40 points (95% CI 0.10 to 0.70)).

    “men on a nutrient-restrictive diet had a 0.40 point increase in cognitive-affective symptom scores (95% CI 0.10 to 0.70) compared with women not following a diet.”

    Humansmales

    Mental health consequences of dietary restriction: increased depressive symptoms in biological men and populations with elevated BMI

    BMJ nutrition, prevention & health3 Jun 2025

Depressive symptoms

upin humans1

1 study

  1. Nutrient restriction increases depressive symptoms in humans (+0.61 points (95% CI 0.13 to 1.10)).

    “nutrient-restricted diet was associated with a 0.61 point increase (95% CI 0.13 to 1.10) in PHQ-9 scores.”

    Humansoverweight individuals

    Mental health consequences of dietary restriction: increased depressive symptoms in biological men and populations with elevated BMI

    BMJ nutrition, prevention & health3 Jun 2025

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