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Nurse-led multidomain intervention

Intervention

1 paper3 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Against: findings that point the other way from most findings on the same outcome.

On aging: the drug’s trials ARN judged to be about aging, of every trial that tests it for any use.

No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

  • 1 lab in 1 country
  • Funder: Zhengzhou University
  • Human trial1

Outcomes

3

Psychological well-being and sensory function

no changein humans1

1 study

  1. Nurse-led multidomain intervention has no effect on psychological well-being and sensory function in humans.

    “no significant changes were found in psychological or sensory domains (P > 0.05).”

    Human trialcommunity-dwelling older adults in China; compared with usual care14-week interventionn = 81

    Impact of a nurse-led multidomain intervention on intrinsic capacity among community-dwelling older adults in China: a cluster randomized trial

    BMC public health31 Aug 2025

Locomotion, cognition, and vitality

upin humans1

1 study

  1. Nurse-led multidomain intervention improves locomotion, cognition, and vitality in humans.

    “Improvements were noted in the locomotion, cognition, and vitality domains (P < 0.05)”

    Human trialcommunity-dwelling older adults in China; compared with usual care14-week interventionn = 81

    Impact of a nurse-led multidomain intervention on intrinsic capacity among community-dwelling older adults in China: a cluster randomized trial

    BMC public health31 Aug 2025

Intrinsic capacity

upin humans1

1 study

  1. Nurse-led multidomain intervention improves intrinsic capacity in humans.

    “The intervention group showed significantly higher IC scores than the control group at both T1 and T2”

    Human trialcommunity-dwelling older adults in China; compared with usual care14 weeks; assessed immediately and one month post-interventionn = 81

    Impact of a nurse-led multidomain intervention on intrinsic capacity among community-dwelling older adults in China: a cluster randomized trial

    BMC public health31 Aug 2025

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