Nociceptin receptor antagonist
1 paper2 findings
- 1 lab in 1 country
- Animals1
Outcomes
2Stem cell differentiation
upin mice1
1 study
Stem cell differentiation
upin mice1
Nociceptin receptor antagonist increases stem cell differentiation in mice.
“accompanied by higher ratios of OLGs/OLG progenitor cells, increased myelination, and reduction of reactive astrocytes.”
Animalsin older mice with EAEbrain
Potential Role of Nociceptin/Orphanin FQ in the Progression of Multiple Sclerosis
bioRxiv8 Jul 2026Preprint
Disease severity
downin mice1
1 study
Disease severity
downin mice1
Nociceptin receptor antagonist decreases disease severity in mice.
“treatment with an antagonist of the Nociceptin receptor (NOR) elicits a regression of clinical scoring”
Animalsin older mice with EAE
Potential Role of Nociceptin/Orphanin FQ in the Progression of Multiple Sclerosis
bioRxiv8 Jul 2026Preprint
Latest
1 in 12 monthsbioRxiv
Potential Role of Nociceptin/Orphanin FQ in the Progression of Multiple Sclerosis
Preprint: experiments in miceMechanisms