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Night shift work cessation

Exposure

1 paper1 finding

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Against: findings that point the other way from most findings on the same outcome.

On aging: the drug’s trials ARN judged to be about aging, of every trial that tests it for any use.

No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

  • 1 lab in 1 country
  • Funder: Istituto Nazionale per l'Assicurazione Contro Gli Infortuni sul Lavoro
  • Humans1

Associations

1

Telomere length

upin humans1

1 study

  1. Night shift work cessation is associated with telomere length in humans (β = 0.01, p=0.001).

    “Additionally, TL increased and AA decreased with each year since night shift cessation (β = 0.01, p=0.001 and β = -0.08, p=0.05, respectively).”

    Humanseach year since night shift cessation

    Impact of night shift work on telomere length and epigenetic age in older workers

    Journal of occupational medicine and toxicology (London, England)1 Oct 2025

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