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Neurotensin

Intervention

1 paper studies it1 more mentions it3 findings

PubChemChEBIMeSH

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funders: Gates Foundation and 5 more
  • Animals1

Outcomes

3

FABP1

upin animals1

1 study

  1. Neurotensin increases FABP1.

    “neurotensin inhibits AMPK and increases FABP1 in small intestinal epithelial cells under conditions of obesity.”

    Animalsunder conditions of obesitysmall intestinal epithelial cells

    Neurotensin inhibits AMPK activity and concurrently enhances FABP1 expression in small intestinal epithelial cells associated with obesity and aging

    Experimental & molecular medicineJun 2, 2025

More on FABP1

AMPK signaling

downin mice1

1 study

  1. Neurotensin inhibits AMPK signaling in mice.

    “neurotensin, a 13-amino-acid gut hormone peptide, enhances small intestinal epithelial cell fatty acid uptake through inhibition of AMPK.”

    Animalssmall intestinal epithelial cells

    Neurotensin inhibits AMPK activity and concurrently enhances FABP1 expression in small intestinal epithelial cells associated with obesity and aging

    Experimental & molecular medicineJun 2, 2025

More on AMPK signaling

Lifespan

downin flies1

1 study

  1. Neurotensin shortens lifespan in flies.

    “overexpressing neurotensin in enteroendocrine cells reduced the lifespan of Drosophila”

    Model organismsin enteroendocrine cells

    Neurotensin inhibits AMPK activity and concurrently enhances FABP1 expression in small intestinal epithelial cells associated with obesity and aging

    Experimental & molecular medicineJun 2, 2025

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