Neural stem cell-derived extracellular vesicles
Neural stem cell-derived extracellular vesicles has been studied in 2 papers since 2022: none in people yet, 1 in animals, 1 review. The research so far is in animals. The newest paper, May 9, 2023: “Neural stem cell-derived extracellular vesicles: mini players with key roles in neurogenesis, immunomodulation, neuroprotection and aging”.
2 papers study it4 findingsUpdated
- 1 lab in 1 country
- Funders: Ministero della Salute and 1 more
- Animals1
What did studies of Neural stem cell-derived extracellular vesicles find?
4Studies of Neural stem cell-derived extracellular vesicles measured 4 outcomes; the most studied are neurogenesis (1 study), adult hippocampal neurogenesis (1) and cell proliferation (1).
neurogenesis
upin reviews1
1 study
neurogenesis
upin reviews1
Neural stem cell-derived extracellular vesicles improve neurogenesis.
“NSPC-derived EVs can play key roles on neurodevelopmental and adult neurogenesis, and they are endowed with neuroprotective and immunomodulatory properties”
Review
Frontiers in molecular biosciences
Adult hippocampal neurogenesis
upin mice1
1 study
Adult hippocampal neurogenesis
upin mice1
Neural stem cell-derived extracellular vesicles improve adult hippocampal neurogenesis in mice.
“intranasal administration of exo-NSPC counteracted the high-fat diet-dependent impairment of adult hippocampal neurogenesis in mice”
Animalsin mice on high-fat diethippocampus
Stem cells (Dayton, Ohio)
Cell proliferation
upin mouse cells1
1 study
Cell proliferation
upin mouse cells1
Neural stem cell-derived extracellular vesicles increase cell proliferation in mouse cells.
“stimulation of NSPCs with NSPC-derived exosomes (exo-NSPC) rescued IRS-1/FoxO activation and counteracted both the reduced proliferation and senescence of stem cells.”
Cellsin insulin-resistant NSPCs
Stem cells (Dayton, Ohio)
Cellular senescence
downin mouse cells1
1 study
Cellular senescence
downin mouse cells1
Neural stem cell-derived extracellular vesicles decrease cellular senescence in mouse cells.
“stimulation of NSPCs with NSPC-derived exosomes (exo-NSPC) rescued IRS-1/FoxO activation and counteracted both the reduced proliferation and senescence of stem cells.”
Cellsin insulin-resistant NSPCs
Stem cells (Dayton, Ohio)