N-3 long-chain polyunsaturated fatty acids

Intervention

1 paper3 findings

  • 1 lab in 1 country
  • Funders: Agencia Canaria de Investigación, Innovación y Sociedad de la Información and 1 more
  • Animals1

Outcomes

3

Lipid raft partitioning of glutamate receptors and acid-sensing ion channels

upin mice1

1 study
  1. N-3 long-chain polyunsaturated fatty acids increase lipid raft partitioning of glutamate receptors and acid-sensing ion channels in mice.

    “Paralleling these findings, lipid rafts accumulated mGluR5, NMDA-R, and ASIC2, and increased their R/NR proportions”

    Animalsdietary supplementationhippocampusfemales

    Molecular and biophysical features of hippocampal "lipid rafts aging" are modified by dietary n-3 long-chain polyunsaturated fatty acids

    Aging cell30 May 2023

Hippocampal lipid raft membrane microviscosity

downin mice1

1 study
  1. N-3 long-chain polyunsaturated fatty acids decrease hippocampal lipid raft membrane microviscosity in mice (Returned to values found in young animals).

    “returned membrane microviscosity to values found in young animals.”

    Animalsdietary supplementationhippocampusfemales

    Molecular and biophysical features of hippocampal "lipid rafts aging" are modified by dietary n-3 long-chain polyunsaturated fatty acids

    Aging cell30 May 2023

Hippocampal lipid raft fatty acid alterations

downin mice1

1 study
  1. N-3 long-chain polyunsaturated fatty acids decrease hippocampal lipid raft fatty acid alterations in mice (Partial reversion).

    “Administration of the n-3 LCPUFA diet caused the partial reversion of fatty acid alterations found in aged mice”

    Animalsdietary supplementationhippocampusfemales

    Molecular and biophysical features of hippocampal "lipid rafts aging" are modified by dietary n-3 long-chain polyunsaturated fatty acids

    Aging cell30 May 2023

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